PO-04-035 LEFT ATRIAL V. RIGHT ATRIAL ELECTROGRAPHIC FLOW CONSISTENCY IN PERSISTENT ATRIAL FIBRILLATION

Arrhythmogenic atrial structural remodeling tends to start near the ostia of pulmonary veins (PVs) and then progress other regions left atrium (LA) before affecting right (RA) in patients with fibrillation (AF). Electrographic Flow (EGF) mapping visualizes global cardiac wavefront propagation real-time. The nature substrate may be assessed flow vectors using electrographic consistency (FC), which is magnitude vector at all points space time. High FC characterizes stable through a particular region endocardium while low indicates more chaotic disorganized propagation. Examine patterns between LA RA among all-comers AF. Data was prospectively collected from paroxysmal, persistent, long-standing persistent AF, who underwent EGF 64-electrode basket catheter ablation for For each patient, series 1 minute recordings were taken post-PVI multiple standardized locations both optimize endocardial coverage. Recordings always occurred prior any EGF-identified source ablations, if clinically relevant sources detected post-PVI. Mean these averaged per recording location atrium. Prospective study 65 enrolled: mean age 63.0 ± 9.4 years, 28% (18/65) female, LAD 44.4 5.6 mm. higher v. (0.60±0.23 0.53±0.19, p=0.026). A linear relationship established means (m=0.51, r=0.42, p=2.0x10-4), suggesting that as decreases LA, only half (51%) much RA. Slope r unaffected by recurrence status patients. Of patients, 12-month post-ablation outcomes available 52: rate 61% (11/18) below 11% (2/18) above atria. With progressive remodeling, lower than RA, reflect pathophysiologically, fibrosis originate spread atria indicate biatrial disease hence worse outcomes. More data required understand utility marker AF disease.